The London consortium for cryo-EM (LonCEM), of which the The DNA Replication Group is a founding member, awarded £3 million to establish a new, state-of-the-art cryo-EM facility at the Francis Crick Institute. The award is part of a larger £20 million investment by the Wellcome Trust in cryo-electron microscopy to support world-leading structural biologists across the United Kingdom.
Sun, J.*, Evrin, C.*, Samel, S. A., Fernández-Cid, A., Riera, A., Kawakami, H., Stillman, B.†, Speck, C.†, Li, H.† (2013). Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA. Nature Structural & Molecular Biology 20, 944-951.
*Shared first authorship; †Corresponding authors
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