Matthew Peach joins the Group
Matthew Peach joins the group as a PhD student. Welcome Matt!
04Oct2021
21Sep2021
VACANCY: Research associate x 2 in biochemistry and structural biology (MED02737)
Reference: MED02737
Date posted: 21 September 2021
Closing date: 19 October 2021
Two full-time research associate positions are available to investigate mechanisms of human DNA replication and their misregulation in cancer employing biochemical and structural or genomic approaches, with the aim of discovering how DNA replication origins are specified (position 1), and how DNA replication is regulated (position 2), to support genome stability and achieve faithful DNA replication. Position 1 requires expertise in biochemistry, while position 2 in cryo-EM.
Job details | Apply
21Sep2021
VACANCY: Research associate in genomics (MED02738)
Reference: MED02738
Date posted: 21 September 2021
Closing date: 19 October 2021
A full-time research associate is available to investigate mechanisms of human DNA replication and their misregulation in cancer employing biochemical and structural or genomic approaches. The successful applicant will employ high resolution genomics (ChIP-Exo or CUT&RUN), proteomic (ChIP-MS) and cell biological approaches to discover novel mechanisms in the function of human DNA replication origins and explore how misregulation of replication origins leads to genomic instability. Expertise in high-resolution genomics and bioinformatic analysis of data is essential.
Job details | Apply
20Aug2021
Ki Him Nicholas Chiang joins the Group
Ki Him Nicholas Chiang, a biotechnology undergraduate at Imperial College London, joins the Group as a summer student intern. Welcome Nick!
23Jun2021
06Feb2021
New Talos F200i microscope
The Institute got a brand new Thermo Scientific™ Talos™ F200i S/TEM microscope and said goodbye to the Philips CM200. A significant and exciting upgrade!
09Nov2020
Josh Tomkins joins the Group
Josh Tomkins joined the Group as a PhD student. Welcome Josh!
05Oct2020
Marina Ivanova and Lepakshi Ranjha join the Group
Marina Ivanova and Lepakshi Ranjha joined the Group as postdoctoral fellows. A big welcome to both!
15Jul2020
New paper on the structural mechanism of helicase loading
Yuan, Z., Schneider, S., Dodd, T., Riera, A., Bai, L., Yan, C., Magdalou, I., Ivanov, I., Stillman, B., Li, H., Speck, C. (2020). Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proceedings of the National Academy of Sciences of the United States of America 117, 17747-17756.
Abstract | Full Text |
07Nov2019
Group awarded BBSRC project grant
The Group's Biotechnology and Biological Sciences Research Council (BBSRC) grant application was successful! Huge congratulations to Sarah Schneider, Almutasem Saleh and Yasunori Noguchi for writing a fantastic proposal and achieving a superb ranking of fourth out of 89. Two new postdoctoral positions will open soon. Interested candidates should contact Christian Speck.
11Oct2019
Data collected using new Titan Krios cryo-TEM
First data collected using the London Consortium for cryo-EM's (LonCEM's) new Titan Krios Cryo Transmission Electron Microscope with the Gatan K3™ camera in super-resolution mode. A dream come true.
30Sep2019
Shenaz Allyjaun and Jessica Ellins join the Group
Shenaz Allyjaun and Jessica Ellins join the Group as PhD students. Welcome Shenaz and Jessica!