23Jun2021
15Jul2020
New paper on the structural mechanism of helicase loading
Yuan, Z., Schneider, S., Dodd, T., Riera, A., Bai, L., Yan, C., Magdalou, I., Ivanov, I., Stillman, B., Li, H., Speck, C. (2020). Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proceedings of the National Academy of Sciences of the United States of America 117, 17747-17756.
Abstract | Full Text |
13Feb2017
15Sep2013
Editorial on pre-RC formation
Riera, A., Li, H., Speck, C. (2013). Seeing is believing: The MCM2–7 helicase trapped in complex with its DNA loader. Cell Cycle 12, 2917-2918.
Full text |
01Aug2013
New paper establishes architecture of the OCCM complex
Sun, J.*, Evrin, C.*, Samel, S. A., Fernández-Cid, A., Riera, A., Kawakami, H., Stillman, B.†, Speck, C.†, Li, H.† (2013). Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA. Nature Structural & Molecular Biology 20, 944-951.
*Shared first authorship; †Corresponding authors
Abstract | Full text | Brookhaven National Laboratory Newsroom |