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New paper proposes lagging-strand DNA extrusion mechanism

Noguchi, Y., Yuan, Z., Bai, L., Schneider, S., Zhao, G., Stillman, B., Speck, C., Li, H. (2017). Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model. Proceedings of the National Academy of Sciences of the United States of America 114, E9529-E9538.
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New cryo-electron microscope produces first beam

The cryo-electron microscope installed on the Imperial College London Hammersmith Campus produces its first beam, coinciding, fittingly, with the award of the 2017 Nobel Prize in Chemistry, to Jacques Dubochet, Joachim Franck and Richard Henderson, “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution.”