Author - SpeckLab

New paper proposes lagging-strand DNA extrusion mechanism

Noguchi, Y., Yuan, Z., Bai, L., Schneider, S., Zhao, G., Stillman, B., Speck, C., Li, H. (2017). Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model. Proceedings of the National Academy of Sciences of the United States of America, (in the Press).
Abstract | Full text |

New cryo-electron microscope produces first beam

The cryo-electron microscope installed on the Imperial College London Hammersmith Campus produces its first beam, coinciding, fittingly, with the award of the 2017 Nobel Prize in Chemistry, to Jacques Dubochet, Joachim Franck and Richard Henderson, “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution.”

New review paper on initiation of DNA replication

Riera, A., Barbon, M., Noguchi, Y., Reuter, L. M., Schneider, S., Speck, C. (2017). From structure to mechanism — understanding initiation of DNA replication. Genes & Development 31, 1073-1078.
Abstract | Full text |

Riera, A., Barbon, M., Noguchi, Y., Reuter, L. M., Schneider, S., Speck, C. (2017). From structure to mechanism — understanding initiation of DNA replication. Genes & Development 31, 1073-1078.
| Abstract | Full text |

Marta Barbon awarded a Higher Education Academy Associate Fellowship

Marta Barbon awarded a Higher Education Academy Associate Fellowship (AFHEA) for successful and effective demonstration of teaching excellence and learning support within the UK Professional Standards Framework (UKPSF) scheme.  Congratulations Marta!